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Science UpdatesA Gene Editing Strategy to Repair Huntington's Defects"A lot more studies would be needed before we can know if disrupting these repeats with a base editor could be a viable therapeutic strategy to treat patients. But being able to illuminate the biological consequences of interrupted repeats is a really useful and important milestone," explained senior study author Dr David Liu. <a href="https://mastodon.social/tags/CRISPR" class="mention hashtag" rel="nofollow noopener" target="_blank">#CRISPR</a> <a href="https://mastodon.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genetics</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#research</a> <a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://mastodon.social/tags/biotechnology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biotechnology</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.social/tags/Huntingtons" class="mention hashtag" rel="nofollow noopener" target="_blank">#Huntingtons</a> <a href="https://www.labroots.com/trending/genetics-and-genomics/29116/gene-editing-strategy-repair-huntington-s-defects" rel="nofollow noopener" translate="no" target="_blank">https://www.labroots.com/trending/genetics-and-genomics/29116/gene-editing-strategy-repair-huntington-s-defects</a>

Global News NationalScientists make surprise finding on what causes Huntington’s disease New research shows that the mutation is harmless for decades, but it quietly grows into a larger mutation and eventually crosses a threshold, generating toxic proteins. <a href="https://mastodon.hongkongers.net/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.hongkongers.net/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#health</a> <a href="https://mastodon.hongkongers.net/tags/disease" class="mention hashtag" rel="nofollow noopener" target="_blank">#disease</a> <a href="https://mastodon.hongkongers.net/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#research</a> <a href="https://mastodon.hongkongers.net/tags/HuntingtonsDisease" class="mention hashtag" rel="nofollow noopener" target="_blank">#HuntingtonsDisease</a> <a href="https://mastodon.hongkongers.net/tags/Huntingtons" class="mention hashtag" rel="nofollow noopener" target="_blank">#Huntingtons</a> <a href="https://globalnews.ca/news/10964360/huntington-disease-cause-new-study/" rel="nofollow noopener" translate="no" target="_blank">https://globalnews.ca/news/10964360/huntington-disease-cause-new-study/</a>

Science Updates"Exon skipping only works if the resulting protein is still functional, so it can't treat every disease with a genetic basis. That's the overall limitation of the approach," noted Professor Pablo Perez-Pinera."But for diseases like <a href="https://mastodon.social/tags/Alzheimer" class="mention hashtag" rel="nofollow noopener" target="_blank">#Alzheimer</a>'s, <a href="https://mastodon.social/tags/Parkinson" class="mention hashtag" rel="nofollow noopener" target="_blank">#Parkinson</a>'s, <a href="https://mastodon.social/tags/Huntingtons" class="mention hashtag" rel="nofollow noopener" target="_blank">#Huntingtons</a>, or Duchenne's muscular dystrophy, this approach holds a lot of potential." <a href="https://mastodon.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genetics</a> <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#health</a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#medicine</a> <a href="https://mastodon.social/tags/biotechnology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biotechnology</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#research</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://www.labroots.com/trending/genetics-and-genomics/28293/gene-editing-prevent-plaque-formation-alzheimer-s" rel="nofollow noopener" translate="no" target="_blank">https://www.labroots.com/trending/genetics-and-genomics/28293/gene-editing-prevent-plaque-formation-alzheimer-s</a>

Science UpdatesWith organoids, researchers aim to bridge the gaps in knowledge that arise from using animals. These are simplified, miniaturized models of human organs that are created by genetically altering cells. Now, they have provided unexpected new insights into Huntington's disease.<a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#research</a> <a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://mastodon.social/tags/Huntingtons" class="mention hashtag" rel="nofollow noopener" target="_blank">#Huntingtons</a> <a href="https://mastodon.social/tags/disease" class="mention hashtag" rel="nofollow noopener" target="_blank">#disease</a> <a href="https://mastodon.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genetics</a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#medicine</a> <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#health</a> <a href="https://www.labroots.com/trending/cell-and-molecular-biology/27673/organoids-reveal-player-huntington-s-disease" rel="nofollow noopener" translate="no" target="_blank">https://www.labroots.com/trending/cell-and-molecular-biology/27673/organoids-reveal-player-huntington-s-disease</a>

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