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United States News BeepNew DMD Therapy Inhibits Glutamate Dehydrogenase 1Credit: Sinhyu / iStock / Getty Images Plus Researchers at the VIB-KU Leuven Center for Brain and Disease… <a href="https://newsbeep.org/tags/NewsBeep" class="mention hashtag" rel="nofollow noopener" target="_blank">#NewsBeep</a> <a href="https://newsbeep.org/tags/News" class="mention hashtag" rel="nofollow noopener" target="_blank">#News</a> <a href="https://newsbeep.org/tags/US" class="mention hashtag" rel="nofollow noopener" target="_blank">#US</a> <a href="https://newsbeep.org/tags/USA" class="mention hashtag" rel="nofollow noopener" target="_blank">#USA</a> <a href="https://newsbeep.org/tags/UnitedStates" class="mention hashtag" rel="nofollow noopener" target="_blank">#UnitedStates</a> <a href="https://newsbeep.org/tags/UnitedStatesOfAmerica" class="mention hashtag" rel="nofollow noopener" target="_blank">#UnitedStatesOfAmerica</a> <a href="https://newsbeep.org/tags/Genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#Genetics</a> <a href="https://newsbeep.org/tags/duchennemusculardystrophy" class="mention hashtag" rel="nofollow noopener" target="_blank">#duchennemusculardystrophy</a> <a href="https://newsbeep.org/tags/enzymes" class="mention hashtag" rel="nofollow noopener" target="_blank">#enzymes</a> <a href="https://newsbeep.org/tags/muscles" class="mention hashtag" rel="nofollow noopener" target="_blank">#muscles</a> <a href="https://newsbeep.org/tags/news" class="mention hashtag" rel="nofollow noopener" target="_blank">#news</a>&features <a href="https://newsbeep.org/tags/Patientcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#Patientcare</a> <a href="https://newsbeep.org/tags/pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#pharmacology</a> <a href="https://newsbeep.org/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#Science</a> <a href="https://newsbeep.org/tags/topics" class="mention hashtag" rel="nofollow noopener" target="_blank">#topics</a> <a href="https://newsbeep.org/tags/translationalresearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#translationalresearch</a> <a href="https://www.newsbeep.com/us/21194/" rel="nofollow noopener" translate="no" target="_blank">https://www.newsbeep.com/us/21194/</a>

UK<a href="https://www.europesays.com/uk/206473/" rel="nofollow noopener" translate="no" target="_blank">https://www.europesays.com/uk/206473/</a> Few shot learning for phenotype-driven diagnosis of patients with rare genetic diseases <a href="https://pubeurope.com/tags/Biomedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biomedicine</a> <a href="https://pubeurope.com/tags/biotechnology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biotechnology</a> <a href="https://pubeurope.com/tags/ComputerScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#ComputerScience</a> <a href="https://pubeurope.com/tags/Diagnosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Diagnosis</a> <a href="https://pubeurope.com/tags/Diseases" class="mention hashtag" rel="nofollow noopener" target="_blank">#Diseases</a> <a href="https://pubeurope.com/tags/general" class="mention hashtag" rel="nofollow noopener" target="_blank">#general</a> <a href="https://pubeurope.com/tags/Genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#Genetics</a> <a href="https://pubeurope.com/tags/HealthCare" class="mention hashtag" rel="nofollow noopener" target="_blank">#HealthCare</a> <a href="https://pubeurope.com/tags/MachineLearning" class="mention hashtag" rel="nofollow noopener" target="_blank">#MachineLearning</a> <a href="https://pubeurope.com/tags/MedicalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#MedicalResearch</a> <a href="https://pubeurope.com/tags/Medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#Medicine</a>/PublicHealth <a href="https://pubeurope.com/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#Science</a> <a href="https://pubeurope.com/tags/TranslationalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#TranslationalResearch</a> <a href="https://pubeurope.com/tags/UK" class="mention hashtag" rel="nofollow noopener" target="_blank">#UK</a> <a href="https://pubeurope.com/tags/UnitedKingdom" class="mention hashtag" rel="nofollow noopener" target="_blank">#UnitedKingdom</a>

SRF IRIS📢 Save the date! Our next IRIS Insights is coming up this Thursday, June 26 at 2:00 PM (CEST).We’re delighted to welcome Prof. Monilola Olayioye, who will speak on: 🎙️ "Tumors in Dishes: New Opportunities for Personalized Medicine"In her talk, Prof. Olayioye will explore how patient-derived tissue samples can be used to advance cancer treatment. She’ll share insights from the 3R-US team on developing human tumor models – often called “tumors in dishes” – and how they are applied in the lab to test new therapies. The talk will also highlight approaches like bioprinting, alternatives to animal testing, and cancer biotherapeutics designed to activate the immune system.🎯 The goal: more personalized and more effective cancer therapies.This is the third talk in our IRIS Insights series, which showcases interdisciplinary research from the IRIS community and provides a space for dialogue across fields.🗓️ Thursday, 26 June 🕑 2:00 PM (CEST) 🔗 Join via Webex – link in bio/comments 🗣️ Language: EnglishWe’re looking forward to an inspiring session and hope to see you online!<a href="https://xn--baw-joa.social/tags/IRISInsights" class="mention hashtag" rel="nofollow noopener" target="_blank">#IRISInsights</a> <a href="https://xn--baw-joa.social/tags/CancerResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#CancerResearch</a> <a href="https://xn--baw-joa.social/tags/3R" class="mention hashtag" rel="nofollow noopener" target="_blank">#3R</a> <a href="https://xn--baw-joa.social/tags/PersonalizedMedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#PersonalizedMedicine</a> <a href="https://xn--baw-joa.social/tags/Bioprinting" class="mention hashtag" rel="nofollow noopener" target="_blank">#Bioprinting</a> <a href="https://xn--baw-joa.social/tags/TumorModels" class="mention hashtag" rel="nofollow noopener" target="_blank">#TumorModels</a> <a href="https://xn--baw-joa.social/tags/ScienceCommunication" class="mention hashtag" rel="nofollow noopener" target="_blank">#ScienceCommunication</a> <a href="https://xn--baw-joa.social/tags/SRFIRIS" class="mention hashtag" rel="nofollow noopener" target="_blank">#SRFIRIS</a> <a href="https://xn--baw-joa.social/tags/UnivStuttgart" class="mention hashtag" rel="nofollow noopener" target="_blank">#UnivStuttgart</a> <a href="https://xn--baw-joa.social/tags/BiomedicalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#BiomedicalResearch</a> <a href="https://xn--baw-joa.social/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunotherapy</a> <a href="https://xn--baw-joa.social/tags/FutureOfMedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#FutureOfMedicine</a> <a href="https://xn--baw-joa.social/tags/TranslationalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#TranslationalResearch</a> <a href="https://xn--baw-joa.social/tags/HumanTissueModels" class="mention hashtag" rel="nofollow noopener" target="_blank">#HumanTissueModels</a> <a href="https://xn--baw-joa.social/tags/NoAnimalTesting" class="mention hashtag" rel="nofollow noopener" target="_blank">#NoAnimalTesting</a> <a href="https://xn--baw-joa.social/tags/OpenScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#OpenScience</a> <a href="https://xn--baw-joa.social/tags/LifeSciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#LifeSciences</a> <a href="https://xn--baw-joa.social/tags/HealthInnovation" class="mention hashtag" rel="nofollow noopener" target="_blank">#HealthInnovation</a> <a href="https://xn--baw-joa.social/tags/AcademicTalk" class="mention hashtag" rel="nofollow noopener" target="_blank">#AcademicTalk</a> <a href="https://xn--baw-joa.social/tags/InterdisciplinaryResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#InterdisciplinaryResearch</a> <a href="https://xn--baw-joa.social/tags/MedicalInnovation" class="mention hashtag" rel="nofollow noopener" target="_blank">#MedicalInnovation</a> <a href="https://xn--baw-joa.social/tags/WomenInScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#WomenInScience</a> <a href="https://xn--baw-joa.social/tags/ScienceEvent" class="mention hashtag" rel="nofollow noopener" target="_blank">#ScienceEvent</a> <a href="https://xn--baw-joa.social/tags/UniversityResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#UniversityResearch</a>IRIS Board of Directors Prof. Dr. André Bächtiger Prof. Dr. Reinhold Bauer Prof. Dr. Sibylle Baumbach Dr. Miriam K. Prof. Dr. <a href="https://forfuture.social/@ai" class="u-url mention" rel="nofollow noopener" target="_blank">@ai</a> Staab Jun.-Prof. Dr. Maria Wirzberger

Europe Says<a href="https://www.europesays.com/1721919/" rel="nofollow noopener" target="_blank">https://www.europesays.com/1721919/</a> A novel translational bioinformatics framework for facilitating multimodal data analyses in preclinical models of neurological injury <a href="https://pubeurope.com/tags/Data" class="mention hashtag" rel="nofollow noopener" target="_blank">#Data</a> <a href="https://pubeurope.com/tags/DataEngineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#DataEngineering</a> <a href="https://pubeurope.com/tags/DataIntegration" class="mention hashtag" rel="nofollow noopener" target="_blank">#DataIntegration</a> <a href="https://pubeurope.com/tags/DataProcessing" class="mention hashtag" rel="nofollow noopener" target="_blank">#DataProcessing</a> <a href="https://pubeurope.com/tags/DataPublicationAndArchiving" class="mention hashtag" rel="nofollow noopener" target="_blank">#DataPublicationAndArchiving</a> <a href="https://pubeurope.com/tags/DataVisualization" class="mention hashtag" rel="nofollow noopener" target="_blank">#DataVisualization</a> <a href="https://pubeurope.com/tags/HumanitiesAndSocialSciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#HumanitiesAndSocialSciences</a> <a href="https://pubeurope.com/tags/MachineLearning" class="mention hashtag" rel="nofollow noopener" target="_blank">#MachineLearning</a> <a href="https://pubeurope.com/tags/multidisciplinary" class="mention hashtag" rel="nofollow noopener" target="_blank">#multidisciplinary</a> <a href="https://pubeurope.com/tags/MultimodalDataProcessing" class="mention hashtag" rel="nofollow noopener" target="_blank">#MultimodalDataProcessing</a> <a href="https://pubeurope.com/tags/PediatricNeurologicalInjury" class="mention hashtag" rel="nofollow noopener" target="_blank">#PediatricNeurologicalInjury</a> <a href="https://pubeurope.com/tags/PreclinicalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#PreclinicalResearch</a> <a href="https://pubeurope.com/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://pubeurope.com/tags/TranslationalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#TranslationalResearch</a>

Europe Says<a href="https://www.europesays.com/1661552/" rel="nofollow noopener" target="_blank">https://www.europesays.com/1661552/</a> Applied body-fluid analysis by wearable devices <a href="https://pubeurope.com/tags/BiomedicalEngineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#BiomedicalEngineering</a> <a href="https://pubeurope.com/tags/Data" class="mention hashtag" rel="nofollow noopener" target="_blank">#Data</a> <a href="https://pubeurope.com/tags/HealthCare" class="mention hashtag" rel="nofollow noopener" target="_blank">#HealthCare</a> <a href="https://pubeurope.com/tags/HumanitiesAndSocialSciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#HumanitiesAndSocialSciences</a> <a href="https://pubeurope.com/tags/multidisciplinary" class="mention hashtag" rel="nofollow noopener" target="_blank">#multidisciplinary</a> <a href="https://pubeurope.com/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://pubeurope.com/tags/TranslationalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#TranslationalResearch</a>

Nicola RomanòNew <a href="https://qoto.org/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#preprint</a> on <a href="https://qoto.org/tags/biorxiv" class="mention hashtag" rel="nofollow noopener" target="_blank">#biorxiv</a>!"Rodent chronic variable stress procedures: a disjunction between stress entity and impact on behaviour"<a href="https://www.biorxiv.org/content/10.1101/2024.07.04.602063v1.full.pdf+html" rel="nofollow noopener" target="_blank">https://www.biorxiv.org/content/10.1101/2024.07.04.602063v1.full.pdf+html</a>We systematically investigated 350+ studies using chronic variable stress procedures in rodents and assessed the characteristics of the procedure (how many stressors they used, and how many different types, and for how long), then measured the reported effect size for those using behavioural tests as an outcome. Some key disconcerting findings from our study - the large majority of articles uses a unique protocol, and articles featuring the same protocol were from the same authors (aside from one case) - 91% of articles don't provide any justification for their choice of procedureThis is scientifically and ethically troubling given CVS procedures deliberately impose suffering to animals.- when looking at the outcome behavioural procedures measured in the studies (some of which impose further stress on the animals) we found very little correlation between effect size and the characteristics (eg length, strength) of the stress protocol. When there was a statistically significant effect, this was generally very small.We conclude "Most of the studies in our review sought evidence for interventions that would prevent or reverse the effects of chronic stress. But if we are to have any confidence that translational CVS studies provide a foundation for potential clinical interventions, we must take an evidence- and ethics-informed approach to their design."<a href="https://qoto.org/tags/chronicVariableStress" class="mention hashtag" rel="nofollow noopener" target="_blank">#chronicVariableStress</a> <a href="https://qoto.org/tags/stress" class="mention hashtag" rel="nofollow noopener" target="_blank">#stress</a> <a href="https://qoto.org/tags/reproducibility" class="mention hashtag" rel="nofollow noopener" target="_blank">#reproducibility</a> <a href="https://qoto.org/tags/ethics" class="mention hashtag" rel="nofollow noopener" target="_blank">#ethics</a> <a href="https://qoto.org/tags/effectSize" class="mention hashtag" rel="nofollow noopener" target="_blank">#effectSize</a> <a href="https://qoto.org/tags/translationalResearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#translationalResearch</a> <a href="https://qoto.org/tags/physiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#physiology</a>

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