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#geneticediting

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Benjamin Carr, Ph.D. 👨🏻‍💻🧬<p><a href="https://hachyderm.io/tags/Embryo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Embryo</span></a> editing debate is back:</p><p>Heritable polygenic editing: next frontier in <a href="https://hachyderm.io/tags/genomic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genomic</span></a> <a href="https://hachyderm.io/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medicine</span></a>?</p><p>In it Visscher suggest editing 10 bits of <a href="https://hachyderm.io/tags/DNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DNA</span></a> could reduce the prevalence of <a href="https://hachyderm.io/tags/Alzheimer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Alzheimer</span></a>’s or <a href="https://hachyderm.io/tags/schizophrenia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>schizophrenia</span></a> by nearly 10-fold. Another 10 edits could diminish coronary artery <a href="https://hachyderm.io/tags/disease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>disease</span></a> more than 30-fold, and 10 more edits could cut type 2 <a href="https://hachyderm.io/tags/diabetes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>diabetes</span></a> by roughly 60-fold.<br>But doing so would be controversial, both at a scientific and moral level. <br><a href="https://www.nature.com/articles/s41586-024-08300-4" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41586-024</span><span class="invisible">-08300-4</span></a> <a href="https://hachyderm.io/tags/genes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genes</span></a> <a href="https://hachyderm.io/tags/genetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genetic</span></a> <a href="https://hachyderm.io/tags/geneticediting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>geneticediting</span></a></p>
GVogeler<p>At the <a href="https://hcommons.social/tags/dayofdh2024" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dayofdh2024</span></a> introducing students on the basics of <a href="https://hcommons.social/tags/textencoding" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>textencoding</span></a> (♥️<a href="https://hcommons.social/tags/unicode" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>unicode</span></a>, <a href="https://hcommons.social/tags/xml" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>xml</span></a>, <span class="h-card" translate="no"><a href="https://hcommons.social/@TEIConsortium" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>TEIConsortium</span></a></span>), <a href="https://hcommons.social/tags/geneticediting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>geneticediting</span></a> , <a href="https://hcommons.social/tags/criticalApparatus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>criticalApparatus</span></a> , managing <a href="https://dhinfra.at" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">dhinfra.at</span><span class="invisible"></span></a> (<a href="https://hcommons.social/tags/gpu" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>gpu</span></a> clusters for the Austrian <a href="https://hcommons.social/tags/dh" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dh</span></a> community), talking about scholarly editing Ceija <a href="https://hcommons.social/tags/Stojka" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Stojka</span></a> notebooks <a href="https://www.ceijastojka.org/12924460-the-notebooks" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ceijastojka.org/12924460-the-n</span><span class="invisible">otebooks</span></a> and chatting with Dominik Kowald from KNOW Center Graz about <a href="https://hcommons.social/tags/recsys" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>recsys</span></a> for DH. Now to preparing my presentation on <a href="https://gams.uni-graz.at/o:voccod" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">gams.uni-graz.at/o:voccod</span><span class="invisible"></span></a> the <a href="https://hcommons.social/tags/SKOS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SKOS</span></a> version Denis Muzerelle's Vocabulaire de la <a href="https://hcommons.social/tags/Codicologie" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Codicologie</span></a> .</p>
PhoenixSerenity<p>Many <a href="https://mastodon.sdf.org/tags/Canadians" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Canadians</span></a> supported <a href="https://mastodon.sdf.org/tags/EugenicPolicies" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EugenicPolicies</span></a> in the early 20th century, including some <a href="https://mastodon.sdf.org/tags/medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medical</span></a> professionals, <a href="https://mastodon.sdf.org/tags/politicians" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>politicians</span></a> &amp; <a href="https://mastodon.sdf.org/tags/feminists" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>feminists</span></a>. <a href="https://mastodon.sdf.org/tags/Alberta" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Alberta</span></a> &amp; <a href="https://mastodon.sdf.org/tags/BritishColumbia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BritishColumbia</span></a> passed <a href="https://mastodon.sdf.org/tags/SexualSterilizationActs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SexualSterilizationActs</span></a>, not repealed til 1970s. <a href="https://mastodon.sdf.org/tags/Eugenics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Eugenics</span></a> have continued into the 21st century, including <a href="https://mastodon.sdf.org/tags/CoercedSterilization" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CoercedSterilization</span></a> of <a href="https://mastodon.sdf.org/tags/IndigenousWomen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IndigenousWomen</span></a> &amp; what some have termed the <a href="https://mastodon.sdf.org/tags/NewEugenics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NewEugenics</span></a> — <a href="https://mastodon.sdf.org/tags/GeneticEditing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GeneticEditing</span></a> &amp; the screening of fetuses for <a href="https://mastodon.sdf.org/tags/disabilities" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>disabilities</span></a>.</p><p><a href="https://www.thecanadianencyclopedia.ca/en/article/eugenics" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">thecanadianencyclopedia.ca/en/</span><span class="invisible">article/eugenics</span></a></p><p><a href="https://mastodon.sdf.org/tags/FactsAboutCanada" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FactsAboutCanada</span></a> <a href="https://mastodon.sdf.org/tags/CanadianHistory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CanadianHistory</span></a> <a href="https://mastodon.sdf.org/tags/Racism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Racism</span></a></p>
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