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#preprint_alert

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Moritz Negwer<p><a href="https://mstdn.science/tags/preprint_alert" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>preprint_alert</span></a> about <a href="https://mstdn.science/tags/astrocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>astrocytes</span></a>, the roadies of the brain!</p><p>PhD student Imke Schuurmans and team have come up with a comprehensive one-step <a href="https://mstdn.science/tags/differentiation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>differentiation</span></a> protocol for turning human <a href="https://mstdn.science/tags/iPSCs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>iPSCs</span></a> directly into functional Astrocytes, and how to co-culture them with induced human neurons on multi-electrode arrays for <a href="https://mstdn.science/tags/electrophysiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>electrophysiology</span></a>.</p><p>From my new group (Nadif Kasri lab <span class="h-card" translate="no"><a href="https://mastodon.nl/@radboudumc" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>radboudumc</span></a></span> <span class="h-card" translate="no"><a href="https://mastodon.social/@DondersInst" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>DondersInst</span></a></span>)</p><p>Preprint: <a href="https://www.biorxiv.org/content/10.1101/2024.03.27.586938v1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.03.27.586938v1</span></a></p><p>Imke's explainer: <a href="https://www.linkedin.com/posts/imke-schuurmans-b713a6105_astrocytes-mea-activity-7180850761176645634-qNVm" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">linkedin.com/posts/imke-schuur</span><span class="invisible">mans-b713a6105_astrocytes-mea-activity-7180850761176645634-qNVm</span></a><br><a href="https://mstdn.science/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>neuroscience</span></a> <a href="https://mstdn.science/tags/cellculture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cellculture</span></a></p>
Pereda Lab<p><a href="https://mstdn.science/tags/preprint_alert" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>preprint_alert</span></a></p><p>Caskin2 is a novel talin and Abi1-binding protein that promotes cell motility<br>Wei Wang, Paul Atherton, Maaike Kreft, Lisa te Molder, Sabine van der Poel, Liesbeth Hoekman, Patrick Celie, Robbie P. Joosten, Reinhard Fässler, Anastassis Perrakis, Arnoud Sonnenberg</p><p>Caskin2 is an scaffold protein that interacts via an LD motif with the rod domain of talin1; mainly with talin's R8 repeat.<br>Caskin2 also associates with Abi1 SH3 domain</p><p><span class="h-card" translate="no"><a href="https://biologists.social/@biorxiv_cellbio" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>biorxiv_cellbio</span></a></span> <br><a href="https://www.biorxiv.org/content/10.1101/2024.03.15.585234v1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.03.15.585234v1</span></a></p>
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