jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97619" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97619</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97619" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97619</span></a></p>
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jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97290" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97290</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97290" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97290</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97031" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97031</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=97031" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=97031</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96653" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96653</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96653" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96653</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96527" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96527</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96527" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96527</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96324" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96324</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=96324" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=96324</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95939" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95939</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95939" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95939</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95680" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95680</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95680" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95680</span></a></p>
jobRxiv<p>Postdoctoral Fellow </p><p>Ruijin Hospital</p><p>The new Frontiers in Therapeutics Research Laboratory is an exciting opportunity to launch your career in translational research.</p><p>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95470" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95470</span></a></p><p><a href="https://mas.to/tags/Cancer_Pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer_Pharmacology</span></a> <a href="https://mas.to/tags/cell_biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cell_biology</span></a> <a href="https://mas.to/tags/lnp_mrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lnp_mrna</span></a> <a href="https://mas.to/tags/protac" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>protac</span></a> <a href="https://mas.to/tags/ScienceJobs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceJobs</span></a> <a href="https://mas.to/tags/hiring" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hiring</span></a> <a href="https://mas.to/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a><br><a href="https://jobrxiv.org/job/ruijin-hospital-27778-postdoctoral-fellow/?feed_id=95470" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jobrxiv.org/job/ruijin-hospita</span><span class="invisible">l-27778-postdoctoral-fellow/?feed_id=95470</span></a></p>
PLOS Biology<p>Targeted protein degradation <a href="https://fediscience.org/tags/PROTAC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PROTAC</span></a> is a promising avenue for drug development. This study shows that alkenyl oxindole compounds act as novel <a href="https://fediscience.org/tags/E3ligase" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>E3ligase</span></a> ligands & recruit the CRL4-DCAF11 E3 <a href="https://fediscience.org/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ubiquitin</span></a> ligase complex for substrate degradation <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3WV1U9q" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3WV1U9q</span><span class="invisible"></span></a></p>
Matthieu Schapira<p><a href="https://fediscience.org/tags/PROTAC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PROTAC</span></a> from @Novartis team recruiting DCAF1, an E3 ligase essential in cancer, rescues BTK degradation in a cell line that acquired resistance to a CRBN-recruiting PROTAC. Great mechanistic PoC, even though overall effect on cell viability is not as pronounced. <a href="https://www.biorxiv.org/content/10.1101/2023.04.09.536153v1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">23.04.09.536153v1</span></a></p>
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