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#structureprediction

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michael<p>6-Mar-2025<br>A new algorithm sheds light on ‘disordered’ <a href="https://mastodon.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>proteins</span></a></p><p>The <a href="https://mastodon.social/tags/IntrinsicallyDisorderedProteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IntrinsicallyDisorderedProteins</span></a> (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making <a href="https://mastodon.social/tags/structurePrediction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>structurePrediction</span></a> particularly challenging. These proteins although exhibit chaotic and ‘disordered’ structures, they still perform essential functions.<br><a href="https://www.eurekalert.org/news-releases/1075837" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">eurekalert.org/news-releases/1</span><span class="invisible">075837</span></a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a></p>
Jinwoo Leem<p>Research Topics of interest:<br />* Protein <a href="https://sigmoid.social/tags/structureprediction" class="mention hashtag" rel="tag">#<span>structureprediction</span></a> - <a href="https://sigmoid.social/tags/antibodies" class="mention hashtag" rel="tag">#<span>antibodies</span></a> and TCRs</p><p>* <a href="https://sigmoid.social/tags/NLP" class="mention hashtag" rel="tag">#<span>NLP</span></a> and <a href="https://sigmoid.social/tags/languages" class="mention hashtag" rel="tag">#<span>languages</span></a> in general. E.g., there are many Korean expressions that I wish I could say in English and vice-versa, and I wonder if LLMs will ever &quot;know&quot; the frustration! (Meta: thinking about this makes me 답답해)</p><p>* Few/zero shot learning, self supervision</p><p>* repertoire scale <a href="https://sigmoid.social/tags/NGS" class="mention hashtag" rel="tag">#<span>NGS</span></a> analyses</p>
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