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DATE: December 19, 2024 at 09:00AM
SOURCE: BioWorld MedTech

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Electrocore powers up with Neurometrix acquisition

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#medtech #electroCore #VagusNerveStimulation #Neuromodulation #ChronicPain #Fibromyalgia #NeuroMetrix @ElectrocoreVNS

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#medtech

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t.coElectrocore powers up with Neurometrix acquisitionBy Annette Boyle

DATE: December 18, 2024 at 07:00PM
SOURCE: BioWorld MedTech

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Electrocore powers up with Neurometrix acquisition

t.co/PB0lMqwxz2

#medtech #electroCore #VagusNerveStimulation #Neuromodulation #ChronicPain #Fibromyalgia #NeuroMetrix @ElectrocoreVNS

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#medtech

Articles can be found by scrolling down the page at bioworld.com/topics/85-bioworl .

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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: nationalpsychologist.com
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t.coElectrocore powers up with Neurometrix acquisitionBy Annette Boyle

Modulation of learning-dependent plasticity in the attention network biorxiv.org/content/10.1101/20 "potential to facilitate targeted cognitive enhancement in both healthy and clinical populations"; #tRNS #NeuroModulation #BCI #NeuroTech #neuroscience

bioRxiv · Modulation of learning-dependent plasticity in the attention networkNeuromodulatory interventions have attracted attention for their potential to enhance cognitive functions, including attention and perceptual learning. However, a comprehensive understanding of how these techniques affect cortical activity and plasticity during learning remains limited. Our previous work has shown that bilateral transcranial random noise stimulation (tRNS) over the intraparietal sulcus (IPS), but not over active control areas, coupled with a multi-session attention-based perceptual learning paradigm increases functional connectivity between nodes of the dorsal attention network (DVAN, Conto' et al., 2021). In this follow-up study we examined the impact of the same multi-session stimulation protocol on BOLD signal modulation in the DVAN during two interleaved attention tasks. Our findings reveal that tRNS targeting the intraparietal sulcus (IPS), a core node of the DVAN, selectively modulates BOLD responses during an orientation discrimination (OD) task, but not during a temporal order judgment (TOJ) task, emphasizing task-specific neural effects. Control analyses within the default mode network (DMN) showed no significant changes, indicating the specificity of tRNS effects on the DVAN. In contrast to existing neuroimaging studies on the cortical response to current stimulation, which often focus on single-session effects, our research measured long-term impacts of multi-session tRNS on cortical dynamics. Notably, we observed a significant increase in BOLD signal in the DVAN during OD following parietal tRNS, with increased beta weights compared to sham or to the human middle temporal area (hMT), our active control stimulation condition. These findings suggest that tRNS, when applied to critical nodes like the IPS, can enhance neural activity across the attention network, thus facilitating task performance. Our results further underscore tRNS's task-selective and network-specific effects, as neural modulation was observed exclusively in the spatial but not in the temporal processing task. The region-specific nature of these effects suggests that tRNS-induced modulation is constrained to key network nodes, enhancing the DVAN's cortical response in spatial tasks, a response that instead decreases after sham and has no benefit on behavior. The selectivity of the response aligns with theories of neural efficiency, indicating that tRNS may prevent natural downregulation in task-relevant areas and promotes sustained plasticity. These findings have important implications for using tRNS in cognitive training, highlighting its potential to facilitate targeted cognitive enhancement in both healthy and clinical populations. ### Competing Interest Statement The authors have declared no competing interest.

DATE: October 10, 2024 at 09:00AM
SOURCE: BioWorld MedTech

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Shiratronics raises $66M for neuromodulation migraine treatment

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#medtech @Shiratronics_i #migraine #neuromodulation

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Articles can be found by scrolling down the page at bioworld.com/topics/85-bioworl .

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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: nationalpsychologist.com
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t.coShiratronics raises $66M for neuromodulation migraine treatmentBy Annette Boyle

DATE: October 09, 2024 at 07:00PM
SOURCE: BioWorld MedTech

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Shiratronics raises $66M for neuromodulation migraine treatment

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#medtech @Shiratronics_i #migraine #neuromodulation

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Articles can be found by scrolling down the page at bioworld.com/topics/85-bioworl .

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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: nationalpsychologist.com
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t.coShiratronics raises $66M for neuromodulation migraine treatmentBy Annette Boyle

🧠 There are so many innovations in innervation!

Steven Veld, Naveen Rao, and I brought an accessible article on neuromodulation techniques to life in NEUROTECH FUTURES!

Here, we discuss various neuromodulation technologies, as well as companies producing them.

⚡️ Neuromodulation goes beyond electrifying!
🧲 Some forms use magnets.
✨ Some modes use photonics.
🤝 Some techniques even shake things up!

#neuromodulation #neurotech #neuroscience #neurotechnology #brainhealth

neurotechnology.substack.com/p

NEUROTECH FUTURES · Nods of Neuromod: Neuromodulation Techniques By Naveen Rao

DATE: September 03, 2024 at 08:00AM
SOURCE: BioWorld MedTech

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Stimvia receives MDR certification for neuromodulation system

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#medtech @stimvia #stimvia #neuromodulation #mdr

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#medtech

Articles can be found by scrolling down the page at bioworld.com/topics/85-bioworl .

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.
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
.
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: nationalpsychologist.com
.
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www.bioworld.comStimvia receives MDR certification for neuromodulation systemBy Shani Alexander

Neuropsychiatry: Bringing a precision approach to the treatment of brain disease giving.massgeneral.org/stories "We think we've identified a biomarker in the brain that is specific for suicide and are developing a rapid treatment (as rapid as just one day) that targets a new brain region and is proving effective in a clinical trial."; #neuromodulation

Massachusetts General Hospital Giving · Neuropsychiatry: Bringing a Precision Approach to the Treatment of Brain DiseasePioneering physician-scientist Joan Camprodon, MD, PhD, MPH, is reintegrating neurology and psychiatry.

DATE: August 30, 2024 at 05:00PM
SOURCE: BioWorld MedTech

Direct article link at end of text block below.

Stimvia receives MDR certification for neuromodulation system

t.co/SmeEUWqFBk

#medtech @stimvia #stimvia #neuromodulation #mdr

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#medtech

Articles can be found by scrolling down the page at bioworld.com/topics/85-bioworl .

-------------------------------------------------

Private, vetted email list for mental health professionals: clinicians-exchange.org
.
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
.
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: nationalpsychologist.com
.
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE:
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-------------------------------------------------

www.bioworld.comStimvia receives MDR certification for neuromodulation systemBy Shani Alexander

#Ultrasound system for precise #neuromodulation of human deep brain circuits biorxiv.org/content/10.1101/20 "we demonstrate the system's ability to selectively modulate the activity of the lateral geniculate nucleus (#LGN) and its functionally connected regions in the visual cortex" #neuroscience

More information in the Twitter/X thread x.com/UCL_Ultrasound/status/17

bioRxiv · Ultrasound system for precise neuromodulation of human deep brain circuitsTranscranial ultrasound stimulation (TUS) has emerged as a promising technique for non-invasive neuromodulation, but current systems lack the precision to target deep brain structures effectively. Here, we introduce an advanced TUS system that achieves unprecedented precision in deep brain neuromodulation. The system features a 256-element, helmet-shaped transducer array operating at 555 kHz, coupled with a stereotactic positioning system, individualised treatment planning, and real-time monitoring using functional MRI. In a series of experiments, we demonstrate the system's ability to selectively modulate the activity of the lateral geniculate nucleus (LGN) and its functionally connected regions in the visual cortex. Participants exhibited significantly increased visual cortex activity during concurrent TUS and visual stimulation, with high reproducibility across individuals. Moreover, a theta-burst TUS protocol induced robust neuromodulatory effects, with decreased visual cortex activity observed for at least 40 minutes post-stimulation. These neuromodulatory effects were specific to the targeted LGN, as confirmed by control experiments. Our findings highlight the potential of this advanced TUS system to non-invasively modulate deep brain circuits with high precision and specificity, offering new avenues for studying brain function and developing targeted therapies for neurological and psychiatric disorders. The unprecedented spatial resolution and prolonged neuromodulatory effects demonstrate the transformative potential of this technology for both research and clinical applications, paving the way for a new era of non-invasive deep brain neuromodulation. ### Competing Interest Statement BET, EM, OW, and MR are authors of or have a financial interest in patent filings related to the technology described in this study. BET is a developer of the commercially available k-Plan treatment planning software used in this study and BET and BTC hold a financial interest in the software. The remaining authors declare no competing interests.

#Ultrasound system for precise #neuromodulation of human deep brain circuits biorxiv.org/content/10.1101/20 "we demonstrate the system's ability to selectively modulate the activity of the lateral geniculate nucleus (LGN) and its functionally connected regions in the visual cortex."

bioRxiv · Ultrasound system for precise neuromodulation of human deep brain circuitsTranscranial ultrasound stimulation (TUS) has emerged as a promising technique for non-invasive neuromodulation, but current systems lack the precision to target deep brain structures effectively. Here, we introduce an advanced TUS system that achieves unprecedented precision in deep brain neuromodulation. The system features a 256-element, helmet-shaped transducer array operating at 555 kHz, coupled with a stereotactic positioning system, individualised treatment planning, and real-time monitoring using functional MRI. In a series of experiments, we demonstrate the system's ability to selectively modulate the activity of the lateral geniculate nucleus (LGN) and its functionally connected regions in the visual cortex. Participants exhibited significantly increased visual cortex activity during concurrent TUS and visual stimulation, with high reproducibility across individuals. Moreover, a theta-burst TUS protocol induced robust neuromodulatory effects, with decreased visual cortex activity observed for at least 40 minutes post-stimulation. These neuromodulatory effects were specific to the targeted LGN, as confirmed by control experiments. Our findings highlight the potential of this advanced TUS system to non-invasively modulate deep brain circuits with high precision and specificity, offering new avenues for studying brain function and developing targeted therapies for neurological and psychiatric disorders. The unprecedented spatial resolution and prolonged neuromodulatory effects demonstrate the transformative potential of this technology for both research and clinical applications, paving the way for a new era of non-invasive deep brain neuromodulation. ### Competing Interest Statement BET, EM, OW, and MR are authors of or have a financial interest in patent filings related to the technology described in this study. BET is a developer of the commercially available k-Plan treatment planning software used in this study and BET and BTC hold a financial interest in the software. The remaining authors declare no competing interests.